PROFHILO｜Reverse Time and Restore Youth by Reactivating Collagen from Within

If You Need to Improve These

Visible neck fine lines

Visible neck fine lines

Dull skin and rough texture

Dull skin and rough texture

Unsatisfied with traditional HIFU or RF results

Unsatisfied with traditional HIFU or RF results

Sagging and loose skin

Sagging and loose skin

CHECK IT!
Noticeable Improvement
Before & After
Before (Neck)
After
Before (Neck)
After

Innovative and Safe Hyaluronic Acid Technology
Activate Your Collagen

PROFHILO

PROFHILO is a next-generation collagen stimulator developed by Swiss pharmaceutical company IBSA. It introduces a new injectable therapy called Bio-Remodeling, and is the world's first treatment to use the NAHYCO® patented technology to deliver high-concentration hyaluronic acid without triggering inflammation. Instead, it directly sends “youth signals” to awaken the skin’s natural regeneration mechanisms.

Non-Filler Design
Hyaluronic Acid That Flows, Not Builds Up

Spreading molecule

PROFHILO offers exceptional diffusion, quickly penetrating the dermis and fat layers after injection. It spreads evenly across the face without creating visible lumps or swelling. The treatment does not alter facial shape or add volume, but instead tightens, smooths, and brightens the skin from within.
This technology is approved in over 80 countries, backed by more than 120 clinical studies confirming its effects, including:

  • Stimulates collagen types I, III, and IV (via fibroblasts)
  • Boosts elastin production, improving sagging and laxity
  • Enhances elastin regeneration by 12 times
  • Truly rebuilds skin condition and support structure

Patented Injection Technique
Targeting the Face and Stubborn Neck Lines

5-point injection for face 10-point injection for neck

PROFHILO uses the patented “5-point BAP injection technique” (Bio Aesthetic Points) for the face—requiring only 5 injection points per side—and a “10-point BAP technique” for the neck, effectively targeting stubborn neck lines that other treatments struggle to improve. The multiple-point approach helps minimize bruising and side effects while ensuring even distribution of hyaluronic acid. Each session takes around 15 minutes, requires no anesthesia, and results in minimal swelling or redness.

A Truly “Time-Reversing” Treatment

Reversing time

Most injectable treatments on the market focus on filling volume or enhancing contours. While they may make you "look younger," they fail to truly address the root of skin aging. PROFHILO is different—it is not about adding volume or puffiness, but about delivering high-concentration, non-crosslinked hyaluronic acid to awaken dormant collagen and elastin production. This leads to full skin renewal by restarting the skin's internal regeneration cycle.
That’s why, after using PROFHILO, the change isn’t about looking puffier—it’s about:

  • Skin becoming radiant, hydrated, and refined
  • Improved skin structure with naturally reduced lines
  • Lighter facial contours without puffiness or stiffness
  • Friends saying you “look better”—but can’t tell what changed

COMPARISON
PROFHILO vs Other Injectable Treatments

Category PROFHILO Traditional Filler Skin Booster
Purpose Collagen & elastin regeneration Volume restoration for wrinkles Surface hydration
Crosslinked Non-crosslinked (naturally metabolized) Crosslinked (may cause sensitivity) Non-crosslinked
Diffusion Even, multi-layer diffusion Localized concentration Epidermal layer penetration
Foreign body sensation None Possible None
Application areas Face, neck, eye area, hands Targeted facial hollows Full face surface
Swelling Minimal to none Depends on injection area Mild stinging sensation
← Swipe table left or right →

PROFHILO
AM I A CANDIDATE?

Icon – Moderate signs of aging

Those with moderate signs of aging

Icon – Loose, dry skin, or loss of elasticity

Those with sagging, dryness, or loss of skin elasticity

Icon – Cannot tolerate filler volume or foreign body sensation

Those who dislike the foreign body feel or volume from traditional fillers

Icon – Prefer a natural look with no downtime

Those seeking a natural glow-up with no puffiness or downtime

PROFHILO
BENEFITS

Dual Regeneration Power: Boosts collagen and elastin 12-fold - ICON

Dual regeneration power: Boosts collagen and elastin 12-fold

1
Natural feel: Non-volumizing injection with no puffiness or hardness - ICON

Natural feel: Non-volumizing injection with no puffiness or hardness

2
High safety & stability: Certified in 80+ countries with IBSA pharmaceutical standards - ICON

High safety & stability: Certified in 80+ countries with IBSA pharmaceutical standards

3
Full-face application: Safe for neck, eye area, and delicate zones - ICON

Full-face application: Safe for neck, eye area, and delicate zones

4

ATTENTION
PROFHILO Treatment Reminders

1

Avoid taking aspirin or anticoagulant medications within one week before the treatment.

2

Inform your provider if you are pregnant, breastfeeding, have severe illness, or are prone to allergies.

3

Swelling usually subsides within 12 hours after injection. Cold compresses may help relieve discomfort.

4

Avoid vigorous massage, exfoliation, or high-temperature environments for 3 days after the treatment.

5

Avoid other HIFU or RF treatments within two weeks. A minimum 2-week interval is recommended.

6

Keep the skin well-hydrated and protected from the sun after treatment to enhance and prolong the results.

FAQ
About PROFHILO

It’s recommended to receive three sessions: the first for foundational treatment, the second 30 days later for reinforcement, and the third after 4–6 months based on your skin condition. Most people notice firmer, more hydrated, and smoother skin after the second session. The third session helps prolong the results, which can last up to 12 months or more.

No. PROFHILO is not a volumizing filler. It doesn’t alter facial volume or shape. Its unique non-crosslinked formula and high spreadability allow it to diffuse naturally within the dermis and fat layers, minimizing nodules and avoiding any foreign body sensation or stiffness.

Clinical studies show that most people experience results lasting 6–12 months, sometimes even longer. The actual duration depends on age, lifestyle, skin condition, and skincare habits. Regular maintenance treatments help prolong the benefits.

Yes. PROFHILO is highly compatible with non-conflicting treatments. Common combinations include:

  • HIFU or RF lifting (recommend 2-week interval)
  • Picosecond lasers / HydraFacial (5–7 day interval)
  • Botulinum toxin or fillers (7–14 day interval)
  • Skin boosters or microneedling (timing per doctor’s advice)

Combination therapies can create synergistic effects but should be planned by a qualified doctor.

It’s generally recommended from age 30 as a preventive and anti-aging treatment. If you’re over 35 and already showing signs like skin laxity, fine lines, or dullness, starting a full course early can effectively reactivate collagen regeneration.

Mild swelling or pinpoint redness may occur, usually fading within 12–48 hours. No downtime is needed—you can wear makeup and return to daily activities immediately. Cold compresses are helpful, but avoid hot compresses, massages, or heat-based activities like saunas or hot yoga right after the treatment.

Traditional collagen injections often contain particulate collagen, which may cause a foreign body sensation and may require allergy testing. Their effects are limited. PROFHILO, on the other hand, is a new-generation regenerative hyaluronic acid treatment made from naturally occurring HA in the body. It spreads efficiently, requires no testing, offers high safety, and stimulates natural collagen production for longer-lasting, more natural results.